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NAD + facilitates cellular energy metabolism NAD + /NADH as hydride-donating coenzyme for metabolism Acting as a coenzyme, NAD + plays pivotal roles in energy metabolism pathways including glycolysis, the TCA cycle, OXPHOS, FAO and alcohol (ethanol) metabolism

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Additionally, PEFs can activate the immune system to promote an immune response against the tumor ( 2.2 The strategies of PEFs in tumor treatment PEFs employs electric field energy to target tumors through diverse implementation approaches tailored to specific therapeutic objectives ( Table 1 )

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